Detection of transient protein folding populations by mass spectrometry.
Hydrogen-deuterium exchange measurements are becoming increasingly important in studies of the dynamics of protein molecules and, particularly, of their folding behavior. Electrospray ionization mass spectrometry (ESI-MS) has been used to obtain the distribution of masses within a population of prot...
Main Authors: | Miranker, A, Robinson, C, Radford, SE, Aplin, RT, Dobson, C |
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Format: | Journal article |
Language: | English |
Published: |
1993
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