Molecular dissection of mammalian RNA polymerase II transcriptional termination.

Transcriptional termination of mammalian RNA polymerase II (Pol II) is an essential but little-understood step in protein-coding gene expression. Mechanistically, termination by all DNA-dependent RNA polymerases can be reduced to two steps, namely release of the RNA transcript and release of the DNA...

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Bibliographic Details
Main Authors: West, S, Proudfoot, N, Dye, M
Format: Journal article
Language:English
Published: 2008