Mutagenically separated PCR assay for rapid detection of M41L and K70R zidovudine resistance mutations in CRF01_AE (subtype E) human immunodeficiency virus type 1.

Mutagenically separated PCR assay for rapid detection of M41L and K70R zidovudine resistance mutations in CRF01_AE (subtype E) human immunodeficiency virus type 1.

A rapid zidovudine (ZDV) resistance genotypic assay was developed based on the mutagenically separated PCR (MS-PCR) technique to detect two ZDV-resistant mutations, M41L and K70R in CRF01_AE (subtype E). Endpoint dilution analysis revealed that the newly constructed MS-PCR assay could successfully d...

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Những tác giả chính: Myint, L, Ariyoshi, K, Yan, H, Frater, A, Auwanit, W, Pathipvanith, P, Yamada, K, Matsuda, M, Chiba, T, Fujita, K, McClure, M, Weber, J, Sugiura, W
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2002

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