A population of CD4hiCD38hi T cells correlates with disease severity in patients with acute malaria

Objective: CD4+ T cells are critical mediators of immunity to Plasmodium spp. infection, but their characteristics during malarial episodes and immunopathology in naturally infected adults are poorly defined. Flow cytometric analysis of PBMCs from patients with either P. falciparum or P. knowlesi ma...

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Autors principals: Apte, SH, Minigo, G, Groves, PL, Spargo, JC, Plebanski, M, Grigg, MJ, Kenangalem, E, Burel, JG, Loughland, JR, Flanagan, KL, Piera, KA, William, T, Price, RN, Woodberry, T, Barber, BE, Anstey, NM, Doolan, DL
Format: Journal article
Idioma:English
Publicat: Wiley 2020