Chemical probes for understudied kinases: challenges and opportunities

Over 20 years after the approval of the first-in-class protein kinase inhibitor imatinib, the biological function of a significant fraction of the human kinome remains poorly understood while most research continues to be focused on few well-validated targets. Given the strong genetic evidence for i...

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Detaylı Bibliyografya
Asıl Yazarlar: Serafim, RAM, Elkins, JM, Zuercher, WJ, Laufer, SA, Gehringer, M
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: American Chemical Society 2021