Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity
<p>Regions of low oxygen (hypoxia) occur in most human solid tumours and correlate with a poor patient prognosis as hypoxic regions are resistant to most cancer therapies and have an increased metastatic potential. Hypoxia is a highly dynamic state, characterised by oxygen fluctuations on the...
প্রধান লেখক: | |
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অন্যান্য লেখক: | |
বিন্যাস: | গবেষণাপত্র |
ভাষা: | English |
প্রকাশিত: |
2020
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বিষয়গুলি: |