Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity

<p>Regions of low oxygen (hypoxia) occur in most human solid tumours and correlate with a poor patient prognosis as hypoxic regions are resistant to most cancer therapies and have an increased metastatic potential. Hypoxia is a highly dynamic state, characterised by oxygen fluctuations on the...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας: Bader, SB
Άλλοι συγγραφείς: Hammond, E
Μορφή: Thesis
Γλώσσα:English
Έκδοση: 2020
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