Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity

<p>Regions of low oxygen (hypoxia) occur in most human solid tumours and correlate with a poor patient prognosis as hypoxic regions are resistant to most cancer therapies and have an increased metastatic potential. Hypoxia is a highly dynamic state, characterised by oxygen fluctuations on the...

Повний опис

Бібліографічні деталі
Автор: Bader, SB
Інші автори: Hammond, E
Формат: Дисертація
Мова:English
Опубліковано: 2020
Предмети: