Negative ions enhance survival of membrane protein complexes

Membrane protein complexes are commonly introduced to the mass spectrometer solubilized in detergent micelles. The collisional activation used to remove the detergent, however, often causes protein unfolding and dissociation. As in the case for soluble proteins, electrospray in the positive ion mode...

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Bibliographic Details
Main Authors: Liko, I, Allison, T, Hopper, J, Benesch, J, Robinson, C
Format: Journal article
Language:English
Published: Springer Verlag 2016