Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.

Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.

In the present study, we analyzed the functional profile of CD8+ T-cell responses directed against autologous transmitted/founder HIV-1 isolates during acute and early infection, and examined whether multifunctionality is required for selection of virus escape mutations. Seven anti-retroviral therap...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ferrari, G, Korber, B, Goonetilleke, N, Liu, M, Turnbull, E, Salazar-Gonzalez, J, Hawkins, N, Self, S, Watson, S, Betts, MR, Gay, C, McGhee, K, Pellegrino, P, Williams, I, Tomaras, G, Haynes, B, Gray, C, Borrow, P, Roederer, M, Mcmichael, A, Weinhold, K
Μορφή: Journal article
Γλώσσα:English
Έκδοση: Public Library of Science 2011

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