Structural features of phenol derivatives determining potency for activation of chloride currents via alpha(1) homomeric and alpha(1)beta heteromeric glycine receptors.

Phenol derivatives constitute a family of neuroactive compounds. The aim of our study was to identify structural features that determine their modulatory effects at glycine receptors. We investigated the effects of four methylated phenol derivatives and two halogenated analogues on chloride inward c...

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Main Authors: Haeseler, G, Ahrens, J, Krampfl, K, Bufler, J, Dengler, R, Hecker, H, Aronson, J, Leuwer, M
格式: Journal article
语言:English
出版: 2005