Durable interactions of T cells with T cell receptor stimuli in the absence of a stable immunological synapse

T cells engage in two modes of interaction with antigen-presenting surfaces: stable synapses and motile kinapses. Although it is surmised that durable interactions of T cells with antigen-presenting cells involve synapses, in situ 3D imaging cannot resolve the mode of interaction. We have establishe...

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Autori principali: Mayya, V, Judokusumo, E, Abu Shah, E, Wiggins, C, Kam, L, Dustin, M
Natura: Journal article
Pubblicazione: Elsevier 2018