PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.

Insulin secretion from pancreatic beta cells is stimulated by glucose metabolism. However, the relative importance of metabolizing glucose via mitochondrial oxidative phosphorylation versus glycolysis for insulin secretion remains unclear. von Hippel-Lindau (VHL) tumor suppressor protein, pVHL, nega...

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Main Authors: Zehetner, J, Danzer, C, Collins, S, Eckhardt, K, Gerber, P, Ballschmieter, P, Galvanovskis, J, Shimomura, K, Ashcroft, F, Thorens, B, Rorsman, P, Krek, W
格式: Journal article
语言:English
出版: 2008