Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis.

BACKGROUND: Metformin is a first-line oral agent used in the treatment of type 2 diabetes, but glycaemic response to this drug is highly variable. Understanding the genetic contribution to metformin response might increase the possibility of personalising metformin treatment. We aimed to establish t...

Полное описание

Библиографические подробности
Главные авторы: Zhou, K, Donnelly, L, Yang, J, Li, M, Deshmukh, H, Van Zuydam, N, Ahlqvist, E, Spencer, C, Groop, L, Morris, A, Colhoun, H, Sham, P, McCarthy, M, Palmer, C, Pearson, E
Формат: Journal article
Язык:English
Опубликовано: 2014