Rhodium catalysed C-3/5 methylation of pyridines using temporary dearomatisation

Rhodium catalysed C-3/5 methylation of pyridines using temporary dearomatisation

Pyridines are ubiquitous aromatic rings used in organic chemistry and are crucial elements of the drug discovery process. Herein we describe a new catalytic method that directly introduces a methyl group onto the aromatic ring; this new reaction is related to hydrogen borrowing, and is notable for i...

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Príomhchruthaitheoirí:	Grosavu, A, Hepburn, H, Bailey, E, Lindsay-Scott, P, Donohoe, T
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Royal Society of Chemistry 2020

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