CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells.

CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells.

CAPS1 and CAPS2 regulate dense-core vesicle release of transmitters and hormones in neuroendocrine cells, but their precise roles in the secretory process remain enigmatic. Here we show that CAPS2(-/-) and CAPS1(+/-);CAPS2(-/-) mice, despite having increased insulin sensitivity, are glucose intolera...

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Bibliographic Details
Main Authors: Speidel, D, Salehi, A, Obermueller, S, Lundquist, I, Brose, N, Renström, E, Rorsman, P
Format: Journal article
Language:English
Published: 2008

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