3-D structural and functional characterization of the purified KATP channel complex Kir6.2-SUR1.

3-D structural and functional characterization of the purified KATP channel complex Kir6.2-SUR1.

ATP-sensitive potassium (K(ATP)) channels conduct potassium ions across cell membranes and thereby couple cellular energy metabolism to membrane electrical activity. Here, we report the heterologous expression and purification of a functionally active K(ATP) channel complex composed of pore-forming...

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Bibliographic Details
Main Authors:	Mikhailov, M, Campbell, J, De Wet, H, Shimomura, K, Zadek, B, Collins, R, Sansom, MS, Ford, R, Ashcroft, F
Format:	Journal article
Language:	English
Published:	2005

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