Resolving heterogeneity in transcranial electrical stimulation efficacy for attention deficit hyperactivity disorder

While the treatment of Attention Deficit Hyperactivity Disorder (ADHD) is dominated by pharmacological agents, transcranial electrical stimulation (tES) is gaining attention as an alternative method for treatment. Most current meta-analyses have suggested that tES can improve cognitive functions tha...

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मुख्य लेखकों: Lipka, R, Ahlers, E-C, Reed, T, Karstens, M, Nguyen, T, Bajbouj, M, Cohen Kadosh, R
स्वरूप: Journal article
भाषा:English
प्रकाशित: Elsevier 2020
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author Lipka, R
Ahlers, E-C
Reed, T
Karstens, M
Nguyen, T
Bajbouj, M
Cohen Kadosh, R
author_facet Lipka, R
Ahlers, E-C
Reed, T
Karstens, M
Nguyen, T
Bajbouj, M
Cohen Kadosh, R
author_sort Lipka, R
collection OXFORD
description While the treatment of Attention Deficit Hyperactivity Disorder (ADHD) is dominated by pharmacological agents, transcranial electrical stimulation (tES) is gaining attention as an alternative method for treatment. Most current meta-analyses have suggested that tES can improve cognitive functions that are otherwise impaired in ADHD, such as inhibition and working memory, as well as alleviated clinical symptoms. Here we review some of the promising findings in the field of tES. At the same time, we highlight two factors, which hinder the effective application of tES in treating ADHD: 1) the heterogeneity of tES protocols used in different studies; 2) patient profiles influencing responses to tES. We highlight potential solutions for overcoming such limitations, including the use of active machine learning, and provide simulated data to demonstrate how these solutions could also improve the understanding, diagnosis, and treatment of ADHD.
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spelling oxford-uuid:7695afc7-3596-4d2e-9f31-8cfcf057b4a52022-03-26T20:17:12ZResolving heterogeneity in transcranial electrical stimulation efficacy for attention deficit hyperactivity disorderJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7695afc7-3596-4d2e-9f31-8cfcf057b4a5EnglishSymplectic ElementsElsevier2020Lipka, RAhlers, E-CReed, TKarstens, MNguyen, TBajbouj, MCohen Kadosh, RWhile the treatment of Attention Deficit Hyperactivity Disorder (ADHD) is dominated by pharmacological agents, transcranial electrical stimulation (tES) is gaining attention as an alternative method for treatment. Most current meta-analyses have suggested that tES can improve cognitive functions that are otherwise impaired in ADHD, such as inhibition and working memory, as well as alleviated clinical symptoms. Here we review some of the promising findings in the field of tES. At the same time, we highlight two factors, which hinder the effective application of tES in treating ADHD: 1) the heterogeneity of tES protocols used in different studies; 2) patient profiles influencing responses to tES. We highlight potential solutions for overcoming such limitations, including the use of active machine learning, and provide simulated data to demonstrate how these solutions could also improve the understanding, diagnosis, and treatment of ADHD.
spellingShingle Lipka, R
Ahlers, E-C
Reed, T
Karstens, M
Nguyen, T
Bajbouj, M
Cohen Kadosh, R
Resolving heterogeneity in transcranial electrical stimulation efficacy for attention deficit hyperactivity disorder
title Resolving heterogeneity in transcranial electrical stimulation efficacy for attention deficit hyperactivity disorder
title_full Resolving heterogeneity in transcranial electrical stimulation efficacy for attention deficit hyperactivity disorder
title_fullStr Resolving heterogeneity in transcranial electrical stimulation efficacy for attention deficit hyperactivity disorder
title_full_unstemmed Resolving heterogeneity in transcranial electrical stimulation efficacy for attention deficit hyperactivity disorder
title_short Resolving heterogeneity in transcranial electrical stimulation efficacy for attention deficit hyperactivity disorder
title_sort resolving heterogeneity in transcranial electrical stimulation efficacy for attention deficit hyperactivity disorder
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