Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients

Fetal haemoglobin (HbF) is a major ameliorating factor in sickle cell disease. We investigated if a quantitative trait locus on chromosome 6q23 was significantly associated with HbF and F cell levels in individuals of African descent. Single nucleotide polymorphisms (SNPs) in a 24-kb intergenic regi...

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Bibliographic Details
Main Authors:	Creary, L, Ulug, P, Menzel, S, McKenzie, C, Hanchard, N, Taylor, V, Farrall, M, Forrester, T, Thein, S
Format:	Journal article
Language:	English
Published:	Public Library of Science 2009
Subjects:	Tropical medicine Genetics (medical sciences) Haematology

Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients. by Creary, L, Ulug, P, Menzel, S, McKenzie, C, Hanchard, N, Taylor, V, Farrall, M, Forrester, T, Thein, S

Published 2009

Journal article

Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients

Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients. by Creary, L, Ulug, P, Menzel, S, McKenzie, C, Hanchard, N, Taylor, V, Farrall, M, Forrester, T, Thein, S

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