Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences

Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences

Despite an unprecedented global research effort on SARS-CoV-2, early replication events remain poorly understood. Given the clinical importance of emergent viral variants with increased transmission, there is an urgent need to understand the early stages of viral replication and transcription. We us...

Полное описание

Библиографические подробности
Главные авторы:	Lee, JY, Wing, PAC, Gala, DS, Noerenberg, M, Järvelin, AI, Titlow, J, Zhuang, X, Palmalux, N, Iselin, L, Thompson, MK, Parton, RM, Prange-Barczynska, M, Wainman, A, Salguero, FJ, Bishop, T, Agranoff, D, James, W, Castello, A, McKeating, JA, Davis, I
Формат:	Journal article
Язык:	English
Опубликовано:	eLife Sciences Publications 2022

Схожие документы

Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
по: Wing, PAC, и др.
Опубликовано: (2022)

The mechanisms of HIF-2α action in the carotid body
по: Prange-Barczyńska, M
Опубликовано: (2022)

Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
по: Wing, PAC, и др.
Опубликовано: (2022)

Hypoxic and pharmacological activation of HIFs inhibits SARS-CoV-2 infection of lung epithelial cells
по: Wing, P, и др.
Опубликовано: (2021)

The new (dis)order in RNA regulation
по: Jarvelin, A, и др.
Опубликовано: (2016)

Cholesterol-modifying drugs in COVID-19
по: Schmidt, NM, и др.
Опубликовано: (2020)

RNA and glia at the Drosophila neuromuscular junction: importance for synaptic plasticity
по: Gala, DS
Опубликовано: (2023)

The role of circadian clock pathways in viral replication
по: Zhuang, X, и др.
Опубликовано: (2022)

The circadian clock and viral infections
по: Borrmann, H, и др.
Опубликовано: (2020)

Oxygen-dependent histone lysine demethylase 4 restricts hepatitis B virus replication
по: Harris, JM, и др.
Опубликовано: (2024)

The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome
по: Tsukuda, S, и др.
Опубликовано: (2024)

Interplay between circadian clock and viral infection
по: Zhuang, X, и др.
Опубликовано: (2017)

Absolute C++ /
по: 233936 Savitch, Walter
Опубликовано: (2006)

Absolute Java /
по: 233936 Savitch, Walter
Опубликовано: (2004)

Absolute analysis /
по: Nevanlinna, F. (Frithiof), 1894-, и др.
Опубликовано: (1973)

Absolute Java /
по: 233936 Savitch, Walter
Опубликовано: (2008)

Absolute Java /
по: 233936 Savitch, Walter, и др.
Опубликовано: (2010)

Absolute rage /
по: 455378 Tanenbaum, Robert K.
Опубликовано: (2002)

Absolute certainty /
по: 170680 Connors, Rose
Опубликовано: (2002)

Super-resolution single molecule fish at the drosophila neuromuscular junction
по: Titlow, J, и др.
Опубликовано: (2018)

Rethinking the Theoretical Foundation of Economics II: Core Themes of the Multilevel Paradigm
по: Snower, DJ, и др.
Опубликовано: (2025)

Time-of-day variation in SARS-CoV-2 RNA levels during the second wave of COVID-19
по: Zhuang, X, и др.
Опубликовано: (2022)

ACIL: analytic class-incremental learning with absolute memorization and privacy protection
по: Zhuang, Huiping, и др.
Опубликовано: (2024)

Daytime variation in hepatitis C virus replication kinetics following liver transplant
по: Zhuang, X, и др.
Опубликовано: (2018)

RNA-binding as a new regulatory dimension in the antiviral innate immune response
по: Iselin, L
Опубликовано: (2024)

Absolute pitch training.
по: Kiehl, John Clark.
Опубликовано: (2023)

Absolute Generality Reconsidered
по: Rayo, Agustin
Опубликовано: (2012)

Absolutely general knowledge
по: Fraser, RE, и др.
Опубликовано: (2020)

Absolute convergence [kasetvideo]
Опубликовано: ([19-)

Absolute convergence [filem]
Опубликовано: ([n d)

Absolutely Basic computing /
по: 170594 Mears, Peter
Опубликовано: (1987)

Absolute and relative generality
по: Studd, JP
Опубликовано: (2013)

The absolute differential calculus /
по: 302504 Levi-Civita, Tullio, и др.
Опубликовано: (1926)

The absolute configuration of curcumalactone /
по: Gao, Ji-Fu

Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection
по: Kamel, W, и др.
Опубликовано: (2021)

Comments on absolute and convective instabilities
по: Ram, A.K., и др.
Опубликовано: (2015)

Absolute calibration of an active antenna
по: Rogers, Alan E.E.
Опубликовано: (2024)

Absolute calibration of an active antenna
по: Rogers, Alan E.E.
Опубликовано: (2024)

Absolute multilateration between spheres
по: Muelaner, J, и др.
Опубликовано: (2017)

On the absolute stereochemistry of pyrinodemin A.
по: Romeril, S, и др.
Опубликовано: (2003)