Combined deficiencies of endosomal ganglioside neuraminidases 3 and 4 in mice cause lysosomal GM3 gangliosidosis

Combined deficiencies of endosomal ganglioside neuraminidases 3 and 4 in mice cause lysosomal GM3 gangliosidosis

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The sialylated glycosphingolipids gangliosides are essential to myelination, axon integrity, transmission of nervous impulses and memory consolidation. Ganglioside expression patterns in the brain are cell-specific, dynamic and maintained by highly coordinated processes of biosynthesis, trafficking,...

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Detalles Bibliográficos
Autores principales:	Pshezhetsky, A, Pan, X, De Aragão, C, Velasco-Martin, J, Priestman, D, Platt, F, Lamarche-Vane, N, Morales, C, Miyagi, T
Formato:	Journal article
Publicado:	Elsevier 2017

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