Immunodominance of cytotoxic T lymphocyte epitopes co-injected in vivo and modulation by interleukin-12.

Immunodominance (ID) of T cell epitopes is a well-documented phenomenon that might have profound significance in the evolution of T cell responses to pathogens, tumors, autoantigens and vaccines. With the intention of developing vaccines composed of several cytotoxic T cell (CTL) epitopes, we inject...

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Autors principals: Eberl, G, Kessler, B, Eberl, L, Brunda, M, Valmori, D, Corradin, G
Format: Journal article
Idioma:English
Publicat: 1996