Genetic diversity and neutral selection in Plasmodium vivax erythrocyte binding protein correlates with patient antigenicity

Genetic diversity and neutral selection in Plasmodium vivax erythrocyte binding protein correlates with patient antigenicity

Plasmodium vivax is the most widespread and difficult to treat cause of human malaria. The development of vaccines against the blood stages of P. vivax remains a key objective for the control and elimination of vivax malaria. Erythrocyte binding-like (EBL) protein family members such as Duffy bindin...

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Hauptverfasser: Han, J-H, Cho, J-S, Ong, JJY, Park, J-H, Nyunt, MH, Sutanto, E, Trimarsanto, H, Petros, B, Aseffa, A, Getachew, S, Sriprawat, K, Anstey, NM, Grigg, MJ, Barber, BE, William, T, Qi, G, Liu, Y, Pearson, RD, Auburn, S, Price, RN, Nosten, F, Rénia, L, Russell, B, Han, E-T
Format: Journal article
Sprache:English
Veröffentlicht: Public Library of Science 2020

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