Nitrogen-containing bisphosphonates of varying antiresorptive potency have been co-crystallized in farnesyl diphosphate synthase and modelled to understand the key structural features involved in enzyme inhibition. - Ebetino, F; Barnett, B; Roze, C; Kashemirov, B; McKenna, C; Evdokimov, A; Pokross, M; Dunford, J; Opermann, U; Kavanagh, K; Rogers, M; Russell, R (2006)