Nitrogen-containing bisphosphonates of varying antiresorptive potency have been co-crystallized in farnesyl diphosphate synthase and modelled to understand the key structural features involved in enzyme inhibition.

Nitrogen-containing bisphosphonates of varying antiresorptive potency have been co-crystallized in farnesyl diphosphate synthase and modelled to understand the key structural features involved in enzyme inhibition.

Detalhes bibliográficos
Principais autores: Ebetino, F, Barnett, B, Roze, C, Kashemirov, B, McKenna, C, Evdokimov, A, Pokross, M, Dunford, J, Opermann, U, Kavanagh, K, Rogers, M, Russell, R
Formato: Conference item
Publicado em: 2006

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