Nitrogen-containing bisphosphonates of varying antiresorptive potency have been co-crystallized in farnesyl diphosphate synthase and modelled to understand the key structural features involved in enzyme inhibition.

Slični predmeti

• Molecular modeling comparison of nitrogen-containing bisphosphonates of varying potency co-crystalized in farnesyl diphosphate synthase
  od: Ebetino, F, i dr.
  Izdano: (2006)
• Human farnesyl diphosphate synthase crystal structures with active and inactive bisphosphonates
  od: Evdokimov, A, i dr.
  Izdano: (2006)
• Molecular modeling comparison of nitrogen-containing bisphosphonates of varying potency co-crystalized in farnesyl diphosphate synthase
  od: Ebetino, F, i dr.
  Izdano: (2006)
• Refining structure activity relationships among nitrogen containing bisphosphonates: Dissociation of mineral binding affinity and inhibitory potency on farnesyl diphosphate synthase.
  od: Xia, Z, i dr.
  Izdano: (2006)
• Molecular interactions of nitrogen-containing bisphosphonates within farnesyl diphosphate synthase
  od: Ebetino, F, i dr.
  Izdano: (2005)