A direct retro-Reformatsky fragmentation: formal ring enlargement of cyclic ketones for novel and practical synthesis of heterocyclic enamines.

A novel and practical synthesis of heterocyclic enamines has been developed from the formal ring enlargement of cyclic ketones, which comprised the retro-Reformatsky fragmentation reaction as a key step. Under alkaline bromination conditions, the Reformatsky adducts derived from five- to seven-membe...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Zhao, M, Wang, M, Yu, C, Huang, Z, Fleet, G
Formaat: Journal article
Taal:English
Gepubliceerd in: 2004