Dectin-1 mediates the biological effects of beta-glucans.

The ability of fungal-derived beta-glucan particles to induce leukocyte activation and the production of inflammatory mediators, such as tumor necrosis factor (TNF)-alpha, is a well characterized phenomenon. Although efforts have been made to understand how these carbohydrate polymers exert their im...

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Bibliographic Details
Main Authors: Brown, G, Herre, J, Williams, D, Willment, J, Marshall, A, Gordon, S
Format: Journal article
Language:English
Published: 2003