Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase.

The susceptibility of the bicyclic nucleoside analogs (BCNAs), highly potent and selective inhibitors of varicella-zoster virus (VZV), to the enzymes involved in nucleoside/nucleobase catabolism has been investigated in comparison with the established anti-VZV agent (E)-5-(2-bromovinyl)-2'-deox...

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Bibliografiska uppgifter
Huvudupphovsmän: Balzarini, J, Sienaert, R, Liekens, S, Van Kuilenburg, A, Carangio, A, Esnouf, R, De Clercq, E, McGuigan, C
Materialtyp: Journal article
Språk:English
Publicerad: 2002