Glucocorticoids inhibit osteoblast proliferation via transcriptional upregulation of MKP-1: A prime target for the development of novel osteo-anabolic agents

Glucocorticoids inhibit osteoblast proliferation via transcriptional upregulation of MKP-1: A prime target for the development of novel osteo-anabolic agents

מידע ביבליוגרפי
Main Authors:	Hulley, P, Horsch, K, De Wet, H, Conradie, M, Langeveldt, C, Hough, F
פורמט:	Conference item
יצא לאור:	2003

פריטים דומים

Rapid inhibitory effects of glucocorticoids on ERK activity and osteoblast proliferation occur via transcriptional upregulation of MKP-1
מאת: Horsch, K, et al.
יצא לאור: (2004)

Rapid inhibitory effects of glucocorticoids on ERK activity and osteoblast proliferation occur via transcriptional upregulation of MKP-1
מאת: Horsch, K, et al.
יצא לאור: (2004)

Vanadate protects osteoblasts in vitro and in vivo from glucocorticoid impairment of proliferation
מאת: Hulley, P, et al.
יצא לאור: (2002)

MKP-1 knockout does not prevent glucocorticoid-induced bone disease in mice.
מאת: Conradie, M, et al.
יצא לאור: (2011)

Glucocorticoids induce rapid up-regulation of mitogen-activated protein kinase phosphatase-1 and dephosphorylation of extracellular signal-regulated kinase and impair proliferation in human and mouse osteoblast cell lines.
מאת: Engelbrecht, Y, et al.
יצא לאור: (2003)

Vanadate prevents glucocorticoid-induced apoptosis of osteoblasts in vitro and osteocytes in vivo.
מאת: Conradie, M, et al.
יצא לאור: (2007)

Glucocorticoid-induced osteoporosis in the rat is prevented by the tyrosine phosphatase inhibitor, sodium orthovanadate.
מאת: Hulley, P, et al.
יצא לאור: (2002)

Mitogen-activated protein kinase phosphatase 1/dual specificity phosphatase 1 mediates glucocorticoid inhibition of osteoblast proliferation.
מאת: Horsch, K, et al.
יצא לאור: (2007)

The tyrosine phosphatase inhibitor vanadate protects osteoblasts from growth inhibition by glucocorticoids.
מאת: Hulley, P, et al.
יצא לאור: (1999)

Alternative insulin signalling pathways in osteoblasts
מאת: Langeveldt, C, et al.
יצא לאור: (2002)

Alternative insulin signalling pathways in osteoblast cell lines
מאת: Langeveldt, C, et al.
יצא לאור: (2002)

Pharmacological estrogen administration causes a FSH-independent osteo-anabolic effect requiring ER alpha in osteoblasts.
מאת: Sebastian Seitz, et al.
יצא לאור: (2012-01-01)

Glucocorticoid transiently upregulates mitochondrial biogenesis in the osteoblast
מאת: Chien-Ning Hsu, et al.
יצא לאור: (2020-01-01)

The identification of transcriptional targets associated with osteoblast apoptosis signaling in response to growth factor withdrawal
מאת: Liang, M, et al.
יצא לאור: (2006)

Regulation of bim in glucocorticoid-mediated osteoblast apoptosis.
מאת: Espina, B, et al.
יצא לאור: (2008)

The BH3-only protein BIM is upregulated in osteoblasts in response to dexamethasone treatment, growth factor deprivation and anoikis
מאת: Espina, B, et al.
יצא לאור: (2005)

Pathogenesis of glucocorticoid osteoporosis: Role of tyrosine phosphatases
מאת: Hulley, P, et al.
יצא לאור: (2001)

BIM is a novel regulator of glucocorticoid-induced apoptosis in osteoblasts
מאת: Espina, B, et al.
יצא לאור: (2006)

Inhibition of mitogen-activated protein kinase activity and proliferation of an early osteoblast cell line (MBA 15.4) by dexamethasone: role of protein phosphatases.
מאת: Hulley, P, et al.
יצא לאור: (1998)

Bim as a potential target in osteoblast survival
מאת: Espina, B, et al.
יצא לאור: (2005)

OsteoBLAST: Computational Routine of Global Molecular Analysis Applied to Biomaterials Development
מאת: Marcel Rodrigues Ferreira, et al.
יצא לאור: (2020-10-01)

Cynarin attenuates LPS-induced endothelial inflammation via upregulation of the negative regulator MKP-3
מאת: Da Bin Kim, et al.
יצא לאור: (2022-05-01)

Regulation of the CCL2 gene in pancreatic β-cells by IL-1β and glucocorticoids: role of MKP-1.
מאת: Susan J Burke, et al.
יצא לאור: (2012-01-01)

Identification of polymorphisms in the MKP1 gene and their association with bone mineral density in men with asthma
מאת: Bassiti, A, et al.
יצא לאור: (2005)

Scoparone attenuates PD-L1 expression in human breast cancer cells by MKP-3 upregulation
מאת: Seung-Woo Kim, et al.
יצא לאור: (2024-12-01)

Stattns: Potential cartilage anabolics?
מאת: Gennero, I, et al.
יצא לאור: (2004)

Anabolic effects and inhibition of interleukin 6 production induced by neridronate on human osteoblasts
מאת: S. Niccolini, et al.
יצא לאור: (2011-09-01)

Randomness improvement of AES using MKP
מאת: Al-Alak, Saif, et al.
יצא לאור: (2013)

Bim is transcriptionally regulated during induction of apoptosis by growth factor withdrawal in osteoblasts
מאת: Liang, M, et al.
יצא לאור: (2007)

MECHANISMS OF OSTEOBLAST INHIBITION BY STEROIDS
מאת: Hulley, P
יצא לאור: (2004)

Comparison of the Anabolic Effects of Reported Osteogenic Compounds on Human Mesenchymal Progenitor-derived Osteoblasts
מאת: Robert Owen, et al.
יצא לאור: (2020-01-01)

Role and regulation of MKP-1 in airway inflammation
מאת: Seyed M. Moosavi, et al.
יצא לאור: (2017-08-01)

TBX3 regulates the transcription of VEGFA to promote osteoblasts proliferation and microvascular regeneration
מאת: Lichuang Wu, et al.
יצא לאור: (2022-07-01)

OsteoKnee®
מאת: Lai, K.W.
יצא לאור: (2015)

Prenatal dexamethasone exposure reduces osteoprogenitor proliferation in mice via histone modifications at the Mkp-1 gene locus
מאת: Yongheng Xie, et al.
יצא לאור: (2024-11-01)

Identification of a Novel Osteogenetic Oligodeoxynucleotide (osteoDN) That Promotes Osteoblast Differentiation in a TLR9-Independent Manner
מאת: Yuma Nihashi, et al.
יצא לאור: (2022-05-01)

Correction: Dose-Dependent Effect of Estrogen Suppresses the Osteo-Adipogenic Transdifferentiation of Osteoblasts via Canonical Wnt Signaling Pathway
יצא לאור: (2014-01-01)

Correction: Dose-Dependent Effect of Estrogen Suppresses the Osteo-Adipogenic Transdifferentiation of Osteoblasts via Canonical Wnt Signaling Pathway.
יצא לאור: (2014-01-01)

Exposure to elevated glucocorticoid during development primes altered transcriptional responses to acute stress in adulthood
מאת: Min-Kyeung Choi, et al.
יצא לאור: (2024-07-01)

Curcumin Inhibits NTHi-Induced MUC5AC Mucin Overproduction in Otitis Media via Upregulation of MAPK Phosphatase MKP-1
מאת: Anuhya Sharma Konduru, et al.
יצא לאור: (2017-01-01)