Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice.

Rheumatoid arthritis is a chronic inflammatory disease associated with certain HLA-DR4 subtypes. The target autoantigen(s) is unknown, but type II collagen (CII) is a candidate, with a single immunodominant DR4-restricted 261-273 T cell epitope (CII(261-273)). In the present study, we have prepared...

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Bibliografische gegevens
Hoofdauteurs: Svendsen, P, Andersen, C, Willcox, N, Coyle, A, Holmdahl, R, Kamradt, T, Fugger, L
Formaat: Journal article
Taal:English
Gepubliceerd in: 2004