Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice.
Rheumatoid arthritis is a chronic inflammatory disease associated with certain HLA-DR4 subtypes. The target autoantigen(s) is unknown, but type II collagen (CII) is a candidate, with a single immunodominant DR4-restricted 261-273 T cell epitope (CII(261-273)). In the present study, we have prepared...
Hoofdauteurs: | , , , , , , |
---|---|
Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
2004
|