The synthesis of deoxygalactostatin and 2,6 imino-heptitol derivatives via stannane mediated hydroxymethylation of 5-azido-1,4-lactones
Deoxygalactostatin, homogalactonojirimycin derivatives and other 2,6-imino-heptitols are accessed via the nucleophilic addition of a hydroxymethyl anion equivalent to 5-azido-1,4-lactones to afford 6-azido-lactols. Subsequent hydrogenation induces intramolecular reductive amination to produce the de...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1998
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