Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency.

Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency.

Ionizing radiation induces clustered DNA damage, which presents a challenge to the cellular repair machinery. The repair efficiency of a single-strand break (SSB) is approximately 4x less than that for repair of an abasic (AP) site when in a bistranded cluster containing 8-oxoG. To explore whether t...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Mourgues, S, Lomax, M, O'Neill, P
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2007

Παρόμοια τεκμήρια

Efficiency of repair of an abasic site within DNA clustered damage sites by mammalian cell nuclear extracts.
ανά: Lomax, M, κ.ά.
Έκδοση: (2004)

8-OxoG retards the activity of the ligase III/XRCC1 complex during the repair of a single-strand break, when present within a clustered DNA damage site.
ανά: Lomax, M, κ.ά.
Έκδοση: (2004)

5,6-Dihydrothymine impairs the base excision repair pathway of a closely opposed AP site or single-strand break.
ανά: Byrne, S, κ.ά.
Έκδοση: (2009)

An oxidized abasic lesion inhibits base excision repair leading to DNA strand breaks in a trinucleotide repeat tract.
ανά: Jill M Beaver, κ.ά.
Έκδοση: (2018-01-01)

Repair of abasic sites in DNA.
ανά: Dianov, G, κ.ά.
Έκδοση: (2003)

Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage.
ανά: Eccles, L, κ.ά.
Έκδοση: (2010)

Biotinylation of Deoxyguanosine at the Abasic Site in Double-Stranded Oligodeoxynucleotides
ανά: Chun Wu
Έκδοση: (2016-01-01)

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ανά: John R Silber, κ.ά.
Έκδοση: (2012-11-01)

Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site.
ανά: Fujimoto, H, κ.ά.
Έκδοση: (2005)

ALKBH1 is dispensable for abasic site cleavage during base excision repair and class switch recombination.
ανά: Tina A Müller, κ.ά.
Έκδοση: (2013-01-01)

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ανά: Kavi P.M. Mehta, κ.ά.
Έκδοση: (2020-06-01)

Restriction-modification system with methyl-inhibited base excision and abasic-site cleavage activities
ανά: Fukuyo, Masaki, κ.ά.
Έκδοση: (2015)

CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair.
ανά: Ström, C, κ.ά.
Έκδοση: (2011)

Repair of oxidative base lesions within clustered DNA damage
ανά: O'Neill, P, κ.ά.
Έκδοση: (2002)

Correction: Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function.
ανά: Zhi Liu, κ.ά.
Έκδοση: (2015-01-01)

Preparation of DNA interstrand cross-link repair intermediates induced by abasic sites
ανά: Jin Tang, κ.ά.
Έκδοση: (2022-01-01)

Interplay of two major repair pathways in the processing of complex double-strand DNA breaks.
ανά: Dobbs, T, κ.ά.
Έκδοση: (2008)

Mcl-1 suppresses abasic site repair following bile acid–induced hepatic cellular DNA damage
ανά: Haiyang Yu, κ.ά.
Έκδοση: (2017-07-01)

Removal of heat-sensitive clustered damaged DNA sites is independent of double-strand break repair.
ανά: Andris Abramenkovs, κ.ά.
Έκδοση: (2018-01-01)

Induction of DNA strand breaks, base lesions and clustered damage sites in hydrated plasmid DNA films by ultrasoft X rays around the phosphorus K edge.
ανά: Yokoya, A, κ.ά.
Έκδοση: (2009)

DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
ανά: Parsons, J, κ.ά.
Έκδοση: (2005)

Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain
ανά: Aris A. Polyzos, κ.ά.
Έκδοση: (2024-09-01)

Photocatalytic Duplex-Based DNAzymes Switched by an Abasic Site
ανά: Longlong Gao, κ.ά.
Έκδοση: (2023-06-01)

Repair of tandem base lesions in DNA by human cell extracts generates persisting single-strand breaks.
ανά: Budworth, H, κ.ά.
Έκδοση: (2005)

Effects of hydration on the induction of strand breaks, base lesions, and clustered damage in DNA films by alpha-radiation
ανά: Yokoya, A, κ.ά.
Έκδοση: (2003)

RAD52 Adjusts Repair of Single-Strand Breaks via Reducing DNA-Damage-Promoted XRCC1/LIG3α Co-localization
ανά: Jian Wang, κ.ά.
Έκδοση: (2021-01-01)

XRCC1 and base excision repair balance in response to nitric oxide
ανά: Svilar, David, κ.ά.
Έκδοση: (2017)

Pathway utilization in response to a site-specific DNA double-strand break in fission yeast.
ανά: Prudden, J, κ.ά.
Έκδοση: (2003)

Laser Microirradiation and Temporal Analysis of XRCC1 Recruitment to Single-strand DNA Breaks
ανά: Anna Campalans, κ.ά.
Έκδοση: (2016-03-01)

The Effects of Molecular Crowding on the Structure and Stability of G-Quadruplexes with an Abasic Site
ανά: Takeshi Fujimoto, κ.ά.
Έκδοση: (2011-01-01)

Correction: Replicative Bypass of Abasic Site in and Human Cells: Similarities and Differences.
Έκδοση: (2014-01-01)

Transcription-associated recombination is independent of XRCC2 and mechanistically separate from homology-directed DNA double-strand break repair
ανά: Savolainen, L, κ.ά.
Έκδοση: (2009)

A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair.
ανά: Taylor, R, κ.ά.
Έκδοση: (2000)

Mechanistic studies of bleomycin-mediated double-stranded DNA cleavage and structural studies of DNA containing normal and 4'-oxidized abasic sites
ανά: Chen, Jingyang, Ph. D. Massachusetts Institute of Technology
Έκδοση: (2008)

Susceptibility to breast cancer and intron 3 Ins/Del genetic polymorphism of DNA double-strand break repair gene XRCC4
ανά: Saadat Mostafa, κ.ά.
Έκδοση: (2015-01-01)

DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics
ανά: Dupradeau, François-Yves, κ.ά.
Έκδοση: (2012)

Analysis of large deletion mutations induced by abasic site analog in human cells
ανά: Tetsuya Suzuki, κ.ά.
Έκδοση: (2018-10-01)

Nucleolytic processing of abasic sites underlies PARP inhibitor hypersensitivity in ALC1-deficient BRCA mutant cancer cells
ανά: Natasha Ramakrishnan, κ.ά.
Έκδοση: (2024-07-01)

XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.
ανά: Dianova, I, κ.ά.
Έκδοση: (2004)

Effect of hydration on the induction of strand breaks and base lesions in plasmid DNA films by gamma-radiation.
ανά: Yokoya, A, κ.ά.
Έκδοση: (2002)