Clostridium difficile surveillance: harnessing new technologies to control transmission.
Clostridium difficile surveillance allows outbreaks of cases clustered in time and space to be identified and further transmission prevented. Traditionally, manual detection of groups of cases diagnosed in the same ward or hospital, often followed by retrospective reference laboratory genotyping, ha...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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2013
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| _version_ | 1797076541900849152 |
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| author | Eyre, D Walker, A |
| author_facet | Eyre, D Walker, A |
| author_sort | Eyre, D |
| collection | OXFORD |
| description | Clostridium difficile surveillance allows outbreaks of cases clustered in time and space to be identified and further transmission prevented. Traditionally, manual detection of groups of cases diagnosed in the same ward or hospital, often followed by retrospective reference laboratory genotyping, has been used to identify outbreaks. However, integrated healthcare databases offer the prospect of automated real-time outbreak detection based on statistically robust methods, and accounting for contacts between cases, including those distant to the ward of diagnosis. Complementary to this, rapid benchtop whole genome sequencing, and other highly discriminatory genotyping, has the potential to distinguish which cases are part of an outbreak with high precision and in clinically relevant timescales. These new technologies are likely to shape future surveillance. |
| first_indexed | 2024-03-07T00:05:12Z |
| format | Journal article |
| id | oxford-uuid:774f89b3-33ca-4d87-8290-3b2dcab73b72 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:05:12Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:774f89b3-33ca-4d87-8290-3b2dcab73b722022-03-26T20:23:03ZClostridium difficile surveillance: harnessing new technologies to control transmission.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:774f89b3-33ca-4d87-8290-3b2dcab73b72EnglishSymplectic Elements at Oxford2013Eyre, DWalker, AClostridium difficile surveillance allows outbreaks of cases clustered in time and space to be identified and further transmission prevented. Traditionally, manual detection of groups of cases diagnosed in the same ward or hospital, often followed by retrospective reference laboratory genotyping, has been used to identify outbreaks. However, integrated healthcare databases offer the prospect of automated real-time outbreak detection based on statistically robust methods, and accounting for contacts between cases, including those distant to the ward of diagnosis. Complementary to this, rapid benchtop whole genome sequencing, and other highly discriminatory genotyping, has the potential to distinguish which cases are part of an outbreak with high precision and in clinically relevant timescales. These new technologies are likely to shape future surveillance. |
| spellingShingle | Eyre, D Walker, A Clostridium difficile surveillance: harnessing new technologies to control transmission. |
| title | Clostridium difficile surveillance: harnessing new technologies to control transmission. |
| title_full | Clostridium difficile surveillance: harnessing new technologies to control transmission. |
| title_fullStr | Clostridium difficile surveillance: harnessing new technologies to control transmission. |
| title_full_unstemmed | Clostridium difficile surveillance: harnessing new technologies to control transmission. |
| title_short | Clostridium difficile surveillance: harnessing new technologies to control transmission. |
| title_sort | clostridium difficile surveillance harnessing new technologies to control transmission |
| work_keys_str_mv | AT eyred clostridiumdifficilesurveillanceharnessingnewtechnologiestocontroltransmission AT walkera clostridiumdifficilesurveillanceharnessingnewtechnologiestocontroltransmission |