Deep brain stimulation for chronic pain
As a clinical intervention, deep brain stimulation (DBS) has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders including chronic pain. In this review, we concentrate on the experience of using DBS to treat chronic pain in Oxford. We provide a...
| Main Authors: | , , , , |
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| Format: | Book section |
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Nova Science Publishers, Inc.
2011
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| _version_ | 1797076543946620928 |
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| author | Kringelbach, M Pereira, E Green, A Owen, S Aziz, T |
| author_facet | Kringelbach, M Pereira, E Green, A Owen, S Aziz, T |
| author_sort | Kringelbach, M |
| collection | OXFORD |
| description | As a clinical intervention, deep brain stimulation (DBS) has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders including chronic pain. In this review, we concentrate on the experience of using DBS to treat chronic pain in Oxford. We provide a brief historical background as well as details of our methods for patient selection, surgical techniques and assessment. While the precise mechanisms of action for DBS remain uncertain, we describe how DBS can help for treatment-resistant chronic pain and have great potential to advance our general understanding of the human brain. In particular, we show how DBS can be used in conjunction with methods such as local field potentials and magnetoencephalography to map the underlying mechanisms of normal and abnormal oscillatory synchronization in the brain related to the pleasure of pain relief. © 2010 by Nova Science Publishers, Inc. All rights reserved. |
| first_indexed | 2024-03-07T00:05:14Z |
| format | Book section |
| id | oxford-uuid:7751a036-3890-4362-8ee9-0056a3f657aa |
| institution | University of Oxford |
| last_indexed | 2024-03-07T00:05:14Z |
| publishDate | 2011 |
| publisher | Nova Science Publishers, Inc. |
| record_format | dspace |
| spelling | oxford-uuid:7751a036-3890-4362-8ee9-0056a3f657aa2022-03-26T20:23:15ZDeep brain stimulation for chronic painBook sectionhttp://purl.org/coar/resource_type/c_3248uuid:7751a036-3890-4362-8ee9-0056a3f657aaSymplectic Elements at OxfordNova Science Publishers, Inc.2011Kringelbach, MPereira, EGreen, AOwen, SAziz, TAs a clinical intervention, deep brain stimulation (DBS) has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders including chronic pain. In this review, we concentrate on the experience of using DBS to treat chronic pain in Oxford. We provide a brief historical background as well as details of our methods for patient selection, surgical techniques and assessment. While the precise mechanisms of action for DBS remain uncertain, we describe how DBS can help for treatment-resistant chronic pain and have great potential to advance our general understanding of the human brain. In particular, we show how DBS can be used in conjunction with methods such as local field potentials and magnetoencephalography to map the underlying mechanisms of normal and abnormal oscillatory synchronization in the brain related to the pleasure of pain relief. © 2010 by Nova Science Publishers, Inc. All rights reserved. |
| spellingShingle | Kringelbach, M Pereira, E Green, A Owen, S Aziz, T Deep brain stimulation for chronic pain |
| title | Deep brain stimulation for chronic pain |
| title_full | Deep brain stimulation for chronic pain |
| title_fullStr | Deep brain stimulation for chronic pain |
| title_full_unstemmed | Deep brain stimulation for chronic pain |
| title_short | Deep brain stimulation for chronic pain |
| title_sort | deep brain stimulation for chronic pain |
| work_keys_str_mv | AT kringelbachm deepbrainstimulationforchronicpain AT pereirae deepbrainstimulationforchronicpain AT greena deepbrainstimulationforchronicpain AT owens deepbrainstimulationforchronicpain AT azizt deepbrainstimulationforchronicpain |