Neuroimaging in dementia.

Dementia is one of the most quickly expanding topics in psychiatric research, while remaining the most frustrating condition to treat. Over the past decade, the genetics and pathophysiology of certain dementias, especially dementia of the Alzheimer type, have been increasingly clarified. However, th...

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Main Authors: Ebmeier, K, Donaghey, C, Dougall, N
Format: Journal article
Language:English
Published: 2005
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author Ebmeier, K
Donaghey, C
Dougall, N
author_facet Ebmeier, K
Donaghey, C
Dougall, N
author_sort Ebmeier, K
collection OXFORD
description Dementia is one of the most quickly expanding topics in psychiatric research, while remaining the most frustrating condition to treat. Over the past decade, the genetics and pathophysiology of certain dementias, especially dementia of the Alzheimer type, have been increasingly clarified. However, the treatment of this condition lags far behind its basic research. Although a number of approaches have been explored, from acetylcholinesterase inhibitors to amyloid vaccinations, the results have been disappointing (Broytman and Malter, 2004; Courtney et al., 2004; Ritchie et al., 2004; Robinson et al., 2004). Neuroimaging has been used in basic clinical research, for diagnostic purposes, or using dementia as a paradigm for local brain lesions to examine normal and disturbed cognitive performance and brain function in parallel. This review will try to give a brief summary of each of these approaches. © 2005 Elsevier Inc. All rights reserved.
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spelling oxford-uuid:775cec5b-72ed-4e95-b89d-8ea67f1a39802022-03-26T20:23:31ZNeuroimaging in dementia.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:775cec5b-72ed-4e95-b89d-8ea67f1a3980EnglishSymplectic Elements at Oxford2005Ebmeier, KDonaghey, CDougall, NDementia is one of the most quickly expanding topics in psychiatric research, while remaining the most frustrating condition to treat. Over the past decade, the genetics and pathophysiology of certain dementias, especially dementia of the Alzheimer type, have been increasingly clarified. However, the treatment of this condition lags far behind its basic research. Although a number of approaches have been explored, from acetylcholinesterase inhibitors to amyloid vaccinations, the results have been disappointing (Broytman and Malter, 2004; Courtney et al., 2004; Ritchie et al., 2004; Robinson et al., 2004). Neuroimaging has been used in basic clinical research, for diagnostic purposes, or using dementia as a paradigm for local brain lesions to examine normal and disturbed cognitive performance and brain function in parallel. This review will try to give a brief summary of each of these approaches. © 2005 Elsevier Inc. All rights reserved.
spellingShingle Ebmeier, K
Donaghey, C
Dougall, N
Neuroimaging in dementia.
title Neuroimaging in dementia.
title_full Neuroimaging in dementia.
title_fullStr Neuroimaging in dementia.
title_full_unstemmed Neuroimaging in dementia.
title_short Neuroimaging in dementia.
title_sort neuroimaging in dementia
work_keys_str_mv AT ebmeierk neuroimagingindementia
AT donagheyc neuroimagingindementia
AT dougalln neuroimagingindementia