Palladium-catalysed ligand-free reductive Heck cycloisomerisation of 1,6-en-α-chloro-enamides

The first example of an intramolecular hydroarylation of 1,6-en-α-chloro-enamides was achieved by a palladium-catalysed ligand-free reductive Heck cycloisomerisation with no competing Heck-cyclised by-product.

Bibliographic Details
Main Authors: Hou, Y, Ma, J, Yang, H, Anderson, E, Whiting, A, Wu, N
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2019
Description
Summary:The first example of an intramolecular hydroarylation of 1,6-en-α-chloro-enamides was achieved by a palladium-catalysed ligand-free reductive Heck cycloisomerisation with no competing Heck-cyclised by-product.