Differences among epitopes recognized by neutralizing antibodies induced by SARS-CoV-2 infection or COVID-19 vaccination

Differences among epitopes recognized by neutralizing antibodies induced by SARS-CoV-2 infection or COVID-19 vaccination

SARS-CoV-2 has gradually acquired amino acid substitutions in its S protein that reduce the potency of neutralizing antibodies, leading to decreased vaccine efficacy. Here, we attempted to obtain mutant viruses by passaging SARS-CoV-2 in the presence of plasma samples from convalescent patients or v...

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Bibliographic Details
Main Authors: Yamamoto, S, Yamayoshi, S, Ito, M, Sakai-Tagawa, Y, Nakachi, I, Baba, R, Kamimoto, S, Ogura, T, Hagiwara, S, Kato, H, Nakajima, H, Uwamino, Y, Yagi, K, Sugaya, N, Nagai, H, Saito, M, Adachi, E, Koga, M, Tsutsumi, T, Duong, C, Okuda, M, Murakami, J, Furusawa, Y, Ujie, M, Iwatsuki-Horimoto, K, Yotsuyanagi, H, Kawaoka, Y
Format: Journal article
Language:English
Published: Cell Press 2023

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