HIV-1 reverse transcriptase: crystallization and analysis of domain structure by limited proteolysis.

HIV-1 reverse transcriptase: crystallization and analysis of domain structure by limited proteolysis.

Bacterially expressed recombinant HIV-1 reverse transcriptase is active as both a homodimer of Mr 66,000 subunits and a heterodimer of Mr 66,000 and 51,000 subunits. The heterodimer is formed by cleavage of a C-terminal fragment from one Mr 66,000 polypeptide, which occurs during purification and cr...

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Bibliographic Details
Main Authors:	Lowe, D, Aitken, A, Bradley, C, Darby, G, Larder, B, Powell, K, Purifoy, D, Tisdale, M, Stammers, D
Format:	Journal article
Language:	English
Published:	1988

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