Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors, following allometric scaling
<p>Microglia arise from the yolk sac and enter the brain during early embryogenesis. Upon entry, microglia undergo <em>in situ</em> proliferation and eventually colonize the entire brain by the third postnatal week in mice. However, the intricacies of their develo...
Main Authors: | Barry-Carroll, L, Greulich, P, Marshall, AR, Riecken, K, Fehse, B, Askew, KE, Li, K, Garaschuk, O, Menassa, DA, Gomez-Nicola, D |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Cell Press
2023
|
Similar Items
-
Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors, following allometric scaling
by: Liam Barry-Carroll, et al.
Published: (2023-05-01) -
Microglial colonisation of the developing brain is facilitated by clonal expansion of highly proliferative progenitors and follows an allometric scaling
by: Barry-Carroll, L, et al.
Published: (2022) -
Coupled proliferation and apoptosis maintain the rapid turnover of microglia in the adult brain.
by: Askew, K, et al.
Published: (2017) -
Multiparameter analysis of timelapse imaging reveals kinetics of megakaryocytic erythroid progenitor clonal expansion and differentiation
by: Vanessa M. Scanlon, et al.
Published: (2022-09-01) -
Changing Functional Signatures of Microglia along the Axis of Brain Aging
by: Bianca Brawek, et al.
Published: (2021-01-01)