Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates.
The development of an efficacious Plasmodium falciparum malaria vaccine remains a top priority for global health. Vaccination with irradiated sporozoites is able to provide complete sterile protection through the action of CD8(+) T cells at the liver-stage of infection. However, this method is curre...
Main Authors: | Longley, R, Salman, A, Cottingham, M, Ewer, K, Janse, C, Khan, S, Spencer, A, Hill, A |
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Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2015
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