Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates.

The development of an efficacious Plasmodium falciparum malaria vaccine remains a top priority for global health. Vaccination with irradiated sporozoites is able to provide complete sterile protection through the action of CD8(+) T cells at the liver-stage of infection. However, this method is curre...

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Príomhchruthaitheoirí: Longley, R, Salman, A, Cottingham, M, Ewer, K, Janse, C, Khan, S, Spencer, A, Hill, A
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Nature Publishing Group 2015