[18F]fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-L-DOPA.
The Ag-mediated electrophilic [(18)F]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [(18)F]selectfluor bis(triflate) in acetone. The process gave 6-[(18)F]fluoro-L-DOPA with a RCY of 19 ± 12% and a specific activity of 2.6 ± 0.3 GBq μmol(-1).
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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| _version_ | 1797076587637637120 |
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| author | Stenhagen, I Kirjavainen, A Forsback, S Jørgensen, C Robins, E Luthra, S Solin, O Gouverneur, V |
| author_facet | Stenhagen, I Kirjavainen, A Forsback, S Jørgensen, C Robins, E Luthra, S Solin, O Gouverneur, V |
| author_sort | Stenhagen, I |
| collection | OXFORD |
| description | The Ag-mediated electrophilic [(18)F]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [(18)F]selectfluor bis(triflate) in acetone. The process gave 6-[(18)F]fluoro-L-DOPA with a RCY of 19 ± 12% and a specific activity of 2.6 ± 0.3 GBq μmol(-1). |
| first_indexed | 2024-03-07T00:05:48Z |
| format | Journal article |
| id | oxford-uuid:77803e87-0968-429d-93d9-064b8af965c3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:05:48Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:77803e87-0968-429d-93d9-064b8af965c32022-03-26T20:24:27Z[18F]fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-L-DOPA.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:77803e87-0968-429d-93d9-064b8af965c3EnglishSymplectic Elements at Oxford2013Stenhagen, IKirjavainen, AForsback, SJørgensen, CRobins, ELuthra, SSolin, OGouverneur, VThe Ag-mediated electrophilic [(18)F]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [(18)F]selectfluor bis(triflate) in acetone. The process gave 6-[(18)F]fluoro-L-DOPA with a RCY of 19 ± 12% and a specific activity of 2.6 ± 0.3 GBq μmol(-1). |
| spellingShingle | Stenhagen, I Kirjavainen, A Forsback, S Jørgensen, C Robins, E Luthra, S Solin, O Gouverneur, V [18F]fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-L-DOPA. |
| title | [18F]fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-L-DOPA. |
| title_full | [18F]fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-L-DOPA. |
| title_fullStr | [18F]fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-L-DOPA. |
| title_full_unstemmed | [18F]fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-L-DOPA. |
| title_short | [18F]fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-L-DOPA. |
| title_sort | 18f fluorination of an arylboronic ester using 18f selectfluor bis triflate application to 6 18f fluoro l dopa |
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