The epidemiology of sickle cell disease in children recruited in infancy in Kilifi, Kenya: A prospective cohort study

The epidemiology of sickle cell disease in children recruited in infancy in Kilifi, Kenya: A prospective cohort study

<p><strong>Background:</strong><br /> Sickle cell disease is the most common severe monogenic disorder in humans. In Africa, 50–90% of children born with sickle cell disease die before they reach their fifth birthday. In this study, we aimed to describe the comparative incide...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Uyoga, S, Macharia, AW, Mochamah, G, Ndila, CM, Nyutu, G, Makale, J, Tendwa, M, Nyatichi, E, Ojal, J, Otiende, M, Shebe, M, Awuondo, KO, Mturi, N, Peshu, N, Tsofa, B, Maitland, K, Scott, JAG, Williams, TN
Materialtyp:	Journal article
Språk:	English
Publicerad:	Elsevier 2019

Liknande verk

The clinical epidemiology of sickle cell anemia In Africa
av: Macharia, AW, et al.
Publicerad: (2017)

Glucose-6-phosphate dehydrogenase deficiency and susceptibility to childhood diseases in Kilifi, Kenya
av: Uyoga, S, et al.
Publicerad: (2020)

The epidemiology of sickle cell disease in children recruited in infancy in Kilifi, Kenya: a prospective cohort study
av: Sophie Uyoga, PhD, et al.
Publicerad: (2019-10-01)

Plasma Plasmodium falciparum Histidine-Rich Protein-2 concentrations in children with malaria infections of differing severity in Kilifi, Kenya
av: Uyoga, S, et al.
Publicerad: (2020)

β-Thalassemia pathogenic variants in a cohort of children from the East African coast
av: Macharia, AW, et al.
Publicerad: (2020)

The indirect health effects of malaria estimated from health advantages of the sickle cell trait
av: Uyoga, S, et al.
Publicerad: (2019)

The population dynamics of haemoglobins A, A2, F and S in the context of the haemoglobinopathies HbS and α+thalassaemia in Kenyan infants
av: Macharia, A, et al.
Publicerad: (2018)

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
av: Ndila, C, et al.
Publicerad: (2018)

The indirect health effects of malaria estimated from health advantages of the sickle cell trait
av: Sophie Uyoga, et al.
Publicerad: (2019-02-01)

The population dynamics of hemoglobins A, A2, F and S in the context of the hemoglobinopathies HbS and α-thalassemia in Kenyan infants
av: Alex W. Macharia, et al.
Publicerad: (2019-05-01)

β‐Thalassemia pathogenic variants in a cohort of children from the East African coast
av: Alexander W. Macharia, et al.
Publicerad: (2020-07-01)

Non-O ABO blood group genotypes differ in their associations with Plasmodium falciparum rosetting and severe malaria
av: Opi, DH, et al.
Publicerad: (2023)

Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision
av: Watson, JA, et al.
Publicerad: (2021)

Excess child mortality after discharge from hospital in Kilifi, Kenya: a retrospective cohort analysis.
av: Moïsi, J, et al.
Publicerad: (2011)

Epistasis between the haptoglobin common variant and α+thalassemia influences risk of severe malaria in Kenyan children
av: Atkinson, S, et al.
Publicerad: (2014)

Epistasis between the haptoglobin common variant and α+thalassemia influences risk of severe malaria in Kenyan children.
av: Atkinson, S, et al.
Publicerad: (2014)

The impact of malaria-protective red blood cell polymorphisms on parasite biomass in children with severe Plasmodium falciparum malaria
av: Uyoga, S, et al.
Publicerad: (2022)

Non-O ABO blood group genotypes differ in their associations with Plasmodium falciparum rosetting and severe malaria.
av: D Herbert Opi, et al.
Publicerad: (2023-09-01)

Causes of death among persons of all ages within the Kilifi Health and Demographic Surveillance System, Kenya, determined from verbal autopsies interpreted using the InterVA-4 model
av: Carolyne Ndila, et al.
Publicerad: (2014-10-01)

Clustering of health risk behaviors among adolescents in Kilifi, Kenya, a rural Sub-Saharan African setting
av: Ssewanyana, D, et al.
Publicerad: (2020)

Profile: The Kilifi Health and Demographic Surveillance System (KHDSS).
av: Scott, J, et al.
Publicerad: (2012)

Observational study: 27 years of severe malaria surveillance in Kilifi, Kenya
av: Patricia Njuguna, et al.
Publicerad: (2019-07-01)

Excess child mortality after discharge from hospital in Kilifi, Kenya: a retrospective cohort analysis
av: Jennifer C Moïsi, et al.

The clinical spectrum of severe childhood malaria in Eastern Uganda
av: Olupot-Olupot, P, et al.
Publicerad: (2020)

Clustering of health risk behaviors among adolescents in Kilifi, Kenya, a rural Sub-Saharan African setting.
av: Derrick Ssewanyana, et al.
Publicerad: (2020-01-01)

Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision
av: James A Watson, et al.
Publicerad: (2021-07-01)

Linking health facility data from young adults aged 18-24 years to longitudinal demographic data: Experience from The Kilifi Health and Demographic Surveillance System
av: Nyundo, C, et al.
Publicerad: (2020)

Invasive Salmonellosis in Kilifi, Kenya.
av: Muthumbi, E, et al.
Publicerad: (2015)

Hepcidin regulation in Kenyan children with severe malaria and non-typhoidal Salmonella bacteremia
av: Abuga, KM, et al.
Publicerad: (2021)

Trends in inpatient and post-discharge mortality among young infants admitted to Kilifi County Hospital, Kenya: a retrospective cohort study
av: Talbert, A, et al.
Publicerad: (2023)

The impact of malaria-protective red blood cell polymorphisms on parasite biomass in children with severe Plasmodium falciparum malaria
av: S. Uyoga, et al.
Publicerad: (2022-06-01)

Assessing the efficiency of catch-up campaigns for the introduction of pneumococcal conjugate vaccine: a modelling study based on data from PCV10 introduction in Kilifi, Kenya
av: Flasche, S, et al.
Publicerad: (2017)

Trends in inpatient and post-discharge mortality among young infants admitted to Kilifi County Hospital, Kenya: a retrospective cohort study
av: Moses Ngari, et al.
Publicerad: (2023-01-01)

Relation between the Dantu blood group variant and bacteremia in Kenyan children: a population-based case-control study
av: Kariuki, SN, et al.
Publicerad: (2024)

No evidence that Knops blood group polymorphisms affect Complement Receptor 1 clustering on Erythrocytes
av: Swann, OV, et al.
Publicerad: (2017)

Age, spatial and temporal variations in hospital admissions with malaria in Kilifi County, Kenya: A 25 year longitudinal observational study
av: Bejon, P, et al.
Publicerad: (2016)

Validating physician-certified verbal autopsy and probabilistic modeling (InterVA) approaches to verbal autopsy interpretation using hospital causes of adult deaths.
av: Bauni, E, et al.
Publicerad: (2011)

Validating physician-certified verbal autopsy and probabilistic modeling (InterVA) approaches to verbal autopsy interpretation using hospital causes of adult deaths
av: Bauni, E, et al.
Publicerad: (2011)

Two complement receptor one alleles have opposing associations with cerebral malaria and interact with α+thalassaemia
av: Herbert Opi, D, et al.
Publicerad: (2018)

BIRC6 modifies risk of invasive bacterial infection in Kenyan children
av: Gilchrist, JJ, et al.
Publicerad: (2022)