Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid

The synthesis of a D-allo-5-(azidomethyl)tetrahydrofuran-2-carboxylate as an amino acid precursor (in which the carboxylic acid is cis to the azidomethyl substituent and trans to the diol moiety) is reported from D-ribose. The oligomerisation of this monomer to dimeric, tetrameric and octameric carb...

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Main Authors: Hungerford, N, Claridge, T, Watterson, M, Aplin, RT, Moreno, A, Fleet, G
Format: Journal article
Language:English
Published: 2000
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author Hungerford, N
Claridge, T
Watterson, M
Aplin, RT
Moreno, A
Fleet, G
author_facet Hungerford, N
Claridge, T
Watterson, M
Aplin, RT
Moreno, A
Fleet, G
author_sort Hungerford, N
collection OXFORD
description The synthesis of a D-allo-5-(azidomethyl)tetrahydrofuran-2-carboxylate as an amino acid precursor (in which the carboxylic acid is cis to the azidomethyl substituent and trans to the diol moiety) is reported from D-ribose. The oligomerisation of this monomer to dimeric, tetrameric and octameric carbopeptoids is described. NMR studies into the solution structures of cyclohexylidene-protected oligomers and of a deprotected tetramer with eight free hydroxy groups are described. © The Royal Society of Chemistry 2000.
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spelling oxford-uuid:77952a1c-852f-44c0-a076-a15329a9e07c2022-03-26T20:25:05ZTetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acidJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:77952a1c-852f-44c0-a076-a15329a9e07cEnglishSymplectic Elements at Oxford2000Hungerford, NClaridge, TWatterson, MAplin, RTMoreno, AFleet, GThe synthesis of a D-allo-5-(azidomethyl)tetrahydrofuran-2-carboxylate as an amino acid precursor (in which the carboxylic acid is cis to the azidomethyl substituent and trans to the diol moiety) is reported from D-ribose. The oligomerisation of this monomer to dimeric, tetrameric and octameric carbopeptoids is described. NMR studies into the solution structures of cyclohexylidene-protected oligomers and of a deprotected tetramer with eight free hydroxy groups are described. © The Royal Society of Chemistry 2000.
spellingShingle Hungerford, N
Claridge, T
Watterson, M
Aplin, RT
Moreno, A
Fleet, G
Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid
title Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid
title_full Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid
title_fullStr Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid
title_full_unstemmed Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid
title_short Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid
title_sort tetrahydrofuran amino acids secondary structure in tetrameric and octameric carbopeptoids derived from a d allo 5 aminomethyl tetrahydrofuran 2 carboxylic acid
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