Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid
The synthesis of a D-allo-5-(azidomethyl)tetrahydrofuran-2-carboxylate as an amino acid precursor (in which the carboxylic acid is cis to the azidomethyl substituent and trans to the diol moiety) is reported from D-ribose. The oligomerisation of this monomer to dimeric, tetrameric and octameric carb...
Main Authors: | , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2000
|
_version_ | 1797076606234132480 |
---|---|
author | Hungerford, N Claridge, T Watterson, M Aplin, RT Moreno, A Fleet, G |
author_facet | Hungerford, N Claridge, T Watterson, M Aplin, RT Moreno, A Fleet, G |
author_sort | Hungerford, N |
collection | OXFORD |
description | The synthesis of a D-allo-5-(azidomethyl)tetrahydrofuran-2-carboxylate as an amino acid precursor (in which the carboxylic acid is cis to the azidomethyl substituent and trans to the diol moiety) is reported from D-ribose. The oligomerisation of this monomer to dimeric, tetrameric and octameric carbopeptoids is described. NMR studies into the solution structures of cyclohexylidene-protected oligomers and of a deprotected tetramer with eight free hydroxy groups are described. © The Royal Society of Chemistry 2000. |
first_indexed | 2024-03-07T00:06:05Z |
format | Journal article |
id | oxford-uuid:77952a1c-852f-44c0-a076-a15329a9e07c |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T00:06:05Z |
publishDate | 2000 |
record_format | dspace |
spelling | oxford-uuid:77952a1c-852f-44c0-a076-a15329a9e07c2022-03-26T20:25:05ZTetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acidJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:77952a1c-852f-44c0-a076-a15329a9e07cEnglishSymplectic Elements at Oxford2000Hungerford, NClaridge, TWatterson, MAplin, RTMoreno, AFleet, GThe synthesis of a D-allo-5-(azidomethyl)tetrahydrofuran-2-carboxylate as an amino acid precursor (in which the carboxylic acid is cis to the azidomethyl substituent and trans to the diol moiety) is reported from D-ribose. The oligomerisation of this monomer to dimeric, tetrameric and octameric carbopeptoids is described. NMR studies into the solution structures of cyclohexylidene-protected oligomers and of a deprotected tetramer with eight free hydroxy groups are described. © The Royal Society of Chemistry 2000. |
spellingShingle | Hungerford, N Claridge, T Watterson, M Aplin, RT Moreno, A Fleet, G Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid |
title | Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid |
title_full | Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid |
title_fullStr | Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid |
title_full_unstemmed | Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid |
title_short | Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo 5-(aminomethyl)tetrahydrofuran-2-carboxylic acid |
title_sort | tetrahydrofuran amino acids secondary structure in tetrameric and octameric carbopeptoids derived from a d allo 5 aminomethyl tetrahydrofuran 2 carboxylic acid |
work_keys_str_mv | AT hungerfordn tetrahydrofuranaminoacidssecondarystructureintetramericandoctamericcarbopeptoidsderivedfromadallo5aminomethyltetrahydrofuran2carboxylicacid AT claridget tetrahydrofuranaminoacidssecondarystructureintetramericandoctamericcarbopeptoidsderivedfromadallo5aminomethyltetrahydrofuran2carboxylicacid AT wattersonm tetrahydrofuranaminoacidssecondarystructureintetramericandoctamericcarbopeptoidsderivedfromadallo5aminomethyltetrahydrofuran2carboxylicacid AT aplinrt tetrahydrofuranaminoacidssecondarystructureintetramericandoctamericcarbopeptoidsderivedfromadallo5aminomethyltetrahydrofuran2carboxylicacid AT morenoa tetrahydrofuranaminoacidssecondarystructureintetramericandoctamericcarbopeptoidsderivedfromadallo5aminomethyltetrahydrofuran2carboxylicacid AT fleetg tetrahydrofuranaminoacidssecondarystructureintetramericandoctamericcarbopeptoidsderivedfromadallo5aminomethyltetrahydrofuran2carboxylicacid |