Standardization of laboratory methods for the PERCH Study.
The Pneumonia Etiology Research for Child Health study was conducted across 7 diverse research sites and relied on standardized clinical and laboratory methods for the accurate and meaningful interpretation of pneumonia etiology data. Blood, respiratory specimens, and urine were collected from child...
Päätekijät: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
Oxford University Press
2017
|
_version_ | 1826279949138395136 |
---|---|
author | Driscoll, AJ Karron, RA Morpeth, SC Bhat, N Levine, OS Baggett, HC Brooks, WA Feikin, DR Hammitt, LL Howie, SRC Knoll, MD Kotloff, KL Madhi, SA Scott, JAG Thea, DM Adrian, PV Ahmed, D Alam, M Anderson, TP Antonio, M Baillie, VL Dione, M Endtz, HP Gitahi, C Karani, A Kwenda, G Maiga, AA McClellan, J Mitchell, JL Morailane, P Mugo, D Mwaba, J Mwansa, J Mwarumba, S Nyongesa, S Panchalingam, S Rahman, M Sawatwong, P Tamboura, B Toure, A Whistler, T O'Brien, KL Murdoch, DR |
author_facet | Driscoll, AJ Karron, RA Morpeth, SC Bhat, N Levine, OS Baggett, HC Brooks, WA Feikin, DR Hammitt, LL Howie, SRC Knoll, MD Kotloff, KL Madhi, SA Scott, JAG Thea, DM Adrian, PV Ahmed, D Alam, M Anderson, TP Antonio, M Baillie, VL Dione, M Endtz, HP Gitahi, C Karani, A Kwenda, G Maiga, AA McClellan, J Mitchell, JL Morailane, P Mugo, D Mwaba, J Mwansa, J Mwarumba, S Nyongesa, S Panchalingam, S Rahman, M Sawatwong, P Tamboura, B Toure, A Whistler, T O'Brien, KL Murdoch, DR |
author_sort | Driscoll, AJ |
collection | OXFORD |
description | The Pneumonia Etiology Research for Child Health study was conducted across 7 diverse research sites and relied on standardized clinical and laboratory methods for the accurate and meaningful interpretation of pneumonia etiology data. Blood, respiratory specimens, and urine were collected from children aged 1-59 months hospitalized with severe or very severe pneumonia and community controls of the same age without severe pneumonia and were tested with an extensive array of laboratory diagnostic tests. A standardized testing algorithm and standard operating procedures were applied across all study sites. Site laboratories received uniform training, equipment, and reagents for core testing methods. Standardization was further assured by routine teleconferences, in-person meetings, site monitoring visits, and internal and external quality assurance testing. Targeted confirmatory testing and testing by specialized assays were done at a central reference laboratory. |
first_indexed | 2024-03-07T00:06:26Z |
format | Journal article |
id | oxford-uuid:77b2f9a3-bc73-495c-a03f-db72bbc37729 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T00:06:26Z |
publishDate | 2017 |
publisher | Oxford University Press |
record_format | dspace |
spelling | oxford-uuid:77b2f9a3-bc73-495c-a03f-db72bbc377292022-03-26T20:26:02ZStandardization of laboratory methods for the PERCH Study.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:77b2f9a3-bc73-495c-a03f-db72bbc37729EnglishSymplectic Elements at OxfordOxford University Press2017Driscoll, AJKarron, RAMorpeth, SCBhat, NLevine, OSBaggett, HCBrooks, WAFeikin, DRHammitt, LLHowie, SRCKnoll, MDKotloff, KLMadhi, SAScott, JAGThea, DMAdrian, PVAhmed, DAlam, MAnderson, TPAntonio, MBaillie, VLDione, MEndtz, HPGitahi, CKarani, AKwenda, GMaiga, AAMcClellan, JMitchell, JLMorailane, PMugo, DMwaba, JMwansa, JMwarumba, SNyongesa, SPanchalingam, SRahman, MSawatwong, PTamboura, BToure, AWhistler, TO'Brien, KLMurdoch, DRThe Pneumonia Etiology Research for Child Health study was conducted across 7 diverse research sites and relied on standardized clinical and laboratory methods for the accurate and meaningful interpretation of pneumonia etiology data. Blood, respiratory specimens, and urine were collected from children aged 1-59 months hospitalized with severe or very severe pneumonia and community controls of the same age without severe pneumonia and were tested with an extensive array of laboratory diagnostic tests. A standardized testing algorithm and standard operating procedures were applied across all study sites. Site laboratories received uniform training, equipment, and reagents for core testing methods. Standardization was further assured by routine teleconferences, in-person meetings, site monitoring visits, and internal and external quality assurance testing. Targeted confirmatory testing and testing by specialized assays were done at a central reference laboratory. |
spellingShingle | Driscoll, AJ Karron, RA Morpeth, SC Bhat, N Levine, OS Baggett, HC Brooks, WA Feikin, DR Hammitt, LL Howie, SRC Knoll, MD Kotloff, KL Madhi, SA Scott, JAG Thea, DM Adrian, PV Ahmed, D Alam, M Anderson, TP Antonio, M Baillie, VL Dione, M Endtz, HP Gitahi, C Karani, A Kwenda, G Maiga, AA McClellan, J Mitchell, JL Morailane, P Mugo, D Mwaba, J Mwansa, J Mwarumba, S Nyongesa, S Panchalingam, S Rahman, M Sawatwong, P Tamboura, B Toure, A Whistler, T O'Brien, KL Murdoch, DR Standardization of laboratory methods for the PERCH Study. |
title | Standardization of laboratory methods for the PERCH Study. |
title_full | Standardization of laboratory methods for the PERCH Study. |
title_fullStr | Standardization of laboratory methods for the PERCH Study. |
title_full_unstemmed | Standardization of laboratory methods for the PERCH Study. |
title_short | Standardization of laboratory methods for the PERCH Study. |
title_sort | standardization of laboratory methods for the perch study |
work_keys_str_mv | AT driscollaj standardizationoflaboratorymethodsfortheperchstudy AT karronra standardizationoflaboratorymethodsfortheperchstudy AT morpethsc standardizationoflaboratorymethodsfortheperchstudy AT bhatn standardizationoflaboratorymethodsfortheperchstudy AT levineos standardizationoflaboratorymethodsfortheperchstudy AT baggetthc standardizationoflaboratorymethodsfortheperchstudy AT brookswa standardizationoflaboratorymethodsfortheperchstudy AT feikindr standardizationoflaboratorymethodsfortheperchstudy AT hammittll standardizationoflaboratorymethodsfortheperchstudy AT howiesrc standardizationoflaboratorymethodsfortheperchstudy AT knollmd standardizationoflaboratorymethodsfortheperchstudy AT kotloffkl standardizationoflaboratorymethodsfortheperchstudy AT madhisa standardizationoflaboratorymethodsfortheperchstudy AT scottjag standardizationoflaboratorymethodsfortheperchstudy AT theadm standardizationoflaboratorymethodsfortheperchstudy AT adrianpv standardizationoflaboratorymethodsfortheperchstudy AT ahmedd standardizationoflaboratorymethodsfortheperchstudy AT alamm standardizationoflaboratorymethodsfortheperchstudy AT andersontp standardizationoflaboratorymethodsfortheperchstudy AT antoniom standardizationoflaboratorymethodsfortheperchstudy AT baillievl standardizationoflaboratorymethodsfortheperchstudy AT dionem standardizationoflaboratorymethodsfortheperchstudy AT endtzhp standardizationoflaboratorymethodsfortheperchstudy AT gitahic standardizationoflaboratorymethodsfortheperchstudy AT karania standardizationoflaboratorymethodsfortheperchstudy AT kwendag standardizationoflaboratorymethodsfortheperchstudy AT maigaaa standardizationoflaboratorymethodsfortheperchstudy AT mcclellanj standardizationoflaboratorymethodsfortheperchstudy AT mitchelljl standardizationoflaboratorymethodsfortheperchstudy AT morailanep standardizationoflaboratorymethodsfortheperchstudy AT mugod standardizationoflaboratorymethodsfortheperchstudy AT mwabaj standardizationoflaboratorymethodsfortheperchstudy AT mwansaj standardizationoflaboratorymethodsfortheperchstudy AT mwarumbas standardizationoflaboratorymethodsfortheperchstudy AT nyongesas standardizationoflaboratorymethodsfortheperchstudy AT panchalingams standardizationoflaboratorymethodsfortheperchstudy AT rahmanm standardizationoflaboratorymethodsfortheperchstudy AT sawatwongp standardizationoflaboratorymethodsfortheperchstudy AT tambourab standardizationoflaboratorymethodsfortheperchstudy AT tourea standardizationoflaboratorymethodsfortheperchstudy AT whistlert standardizationoflaboratorymethodsfortheperchstudy AT obrienkl standardizationoflaboratorymethodsfortheperchstudy AT murdochdr standardizationoflaboratorymethodsfortheperchstudy |