Review. SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator.

SUR1 is an ATP-binding cassette (ABC) transporter with a novel function. In contrast to other ABC proteins, it serves as the regulatory subunit of an ion channel. The ATP-sensitive (KATP) channel is an octameric complex of four pore-forming Kir6.2 subunits and four regulatory SUR1 subunits, and it l...

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Bibliografske podrobnosti
Main Authors: Aittoniemi, J, Fotinou, C, Craig, T, De Wet, H, Proks, P, Ashcroft, F
Format: Journal article
Jezik:English
Izdano: 2009