Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis.

Fourteen patients with multiple sclerosis were treated with the humanized monoclonal antibody CAMPATH-1H which targets the CD52 antigen present on all lymphocytes and some monocytes; four also received anti-CD4 antibody. Lymphopaenia developed rapidly and was sustained for at least 1 year. In 12 pat...

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Hlavní autoři: Moreau, T, Coles, A, Wing, M, Isaacs, J, Hale, G, Waldmann, H, Compston, A
Médium: Journal article
Jazyk:English
Vydáno: 1996