Enantioselective organocatalytic aldol reaction of ynones and its synthetic applications.

[Structure: see text] For the first time, unmodified ynones were used in organocatalytic asymmetric aldol reactions delivering monoprotected anti-alpha,beta-dihydroxyynones in high yields, dr's up to 19:1, and ee's up to 95%. These products can be either reduced to afford enantioenriched u...

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Những tác giả chính: Silva, F, Sawicki, M, Gouverneur, V
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2006