Skeletal muscle mass reference curves for children and adolescents.
BACKGROUND: Skeletal muscle is key to motor development and represents a major metabolic end organ that aids glycaemic regulation. OBJECTIVES: To create gender-specific reference curves for fat-free mass (FFM) and appendicular (limb) skeletal muscle mass (SMMa) in children and adolescents. To examin...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2014
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| _version_ | 1797076678209437696 |
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| author | McCarthy, H Samani-Radia, D Jebb, SA Prentice, A |
| author_facet | McCarthy, H Samani-Radia, D Jebb, SA Prentice, A |
| author_sort | McCarthy, H |
| collection | OXFORD |
| description | BACKGROUND: Skeletal muscle is key to motor development and represents a major metabolic end organ that aids glycaemic regulation. OBJECTIVES: To create gender-specific reference curves for fat-free mass (FFM) and appendicular (limb) skeletal muscle mass (SMMa) in children and adolescents. To examine the muscle-to-fat ratio in relation to body mass index (BMI) for age and gender. METHODS: Body composition was measured by segmental bioelectrical impedance (BIA, Tanita BC418) in 1985 Caucasian children aged 5-18.8 years. Skeletal muscle mass data from the four limbs were used to derive smoothed centile curves and the muscle-to-fat ratio. RESULTS: The centile curves illustrate the developmental patterns of %FFM and SMMa. While the %FFM curves differ markedly between boys and girls, the SMMa (kg), %SMMa and %SMMa/FFM show some similarities in shape and variance, together with some gender-specific characteristics. Existing BMI curves do not reveal these gender differences. Muscle-to-fat ratio showed a very wide range with means differing between boys and girls and across fifths of BMI z-score. CONCLUSIONS: BIA assessment of %FFM and SMMa represents a significant advance in nutritional assessment since these body composition components are associated with metabolic health. Muscle-to-fat ratio has the potential to provide a better index of future metabolic health. |
| first_indexed | 2024-03-07T00:07:09Z |
| format | Journal article |
| id | oxford-uuid:77ec6fdb-577e-4cfc-906a-d4e1cd33bcae |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:07:09Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | oxford-uuid:77ec6fdb-577e-4cfc-906a-d4e1cd33bcae2022-03-26T20:27:21ZSkeletal muscle mass reference curves for children and adolescents.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:77ec6fdb-577e-4cfc-906a-d4e1cd33bcaeEnglishSymplectic Elements at Oxford2014McCarthy, HSamani-Radia, DJebb, SAPrentice, ABACKGROUND: Skeletal muscle is key to motor development and represents a major metabolic end organ that aids glycaemic regulation. OBJECTIVES: To create gender-specific reference curves for fat-free mass (FFM) and appendicular (limb) skeletal muscle mass (SMMa) in children and adolescents. To examine the muscle-to-fat ratio in relation to body mass index (BMI) for age and gender. METHODS: Body composition was measured by segmental bioelectrical impedance (BIA, Tanita BC418) in 1985 Caucasian children aged 5-18.8 years. Skeletal muscle mass data from the four limbs were used to derive smoothed centile curves and the muscle-to-fat ratio. RESULTS: The centile curves illustrate the developmental patterns of %FFM and SMMa. While the %FFM curves differ markedly between boys and girls, the SMMa (kg), %SMMa and %SMMa/FFM show some similarities in shape and variance, together with some gender-specific characteristics. Existing BMI curves do not reveal these gender differences. Muscle-to-fat ratio showed a very wide range with means differing between boys and girls and across fifths of BMI z-score. CONCLUSIONS: BIA assessment of %FFM and SMMa represents a significant advance in nutritional assessment since these body composition components are associated with metabolic health. Muscle-to-fat ratio has the potential to provide a better index of future metabolic health. |
| spellingShingle | McCarthy, H Samani-Radia, D Jebb, SA Prentice, A Skeletal muscle mass reference curves for children and adolescents. |
| title | Skeletal muscle mass reference curves for children and adolescents. |
| title_full | Skeletal muscle mass reference curves for children and adolescents. |
| title_fullStr | Skeletal muscle mass reference curves for children and adolescents. |
| title_full_unstemmed | Skeletal muscle mass reference curves for children and adolescents. |
| title_short | Skeletal muscle mass reference curves for children and adolescents. |
| title_sort | skeletal muscle mass reference curves for children and adolescents |
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